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Table 2 Selection of genes modulated at least 2 fold after E-cadherin and/or P-cadherin induction with respect to control cells.

From: Functional characterization of E- and P-cadherin in invasive breast cancer cells

GenBank accession # Gene Symbol Description Mean E-cadh Mean P-cadh
Cellular adhesion and Extracellular Matrix
AA865745 CDH18 Cadherin 18, type 2 2.07 1.09
AI003692 CDH4 Cadherin 4, R-cadherin (retinal) 2.03 -1.20
H11732 CLECSF2 C-type lectin domain 2, member B 4.45 3.86
AA478481 COL12A1 Collagen, type XII, alpha 1 2.90 2.01
AW467461 ITGB2 Integrin beta 2 -2.28 -1.98
N33214 MMP14 Matrix metalloproteinase 14 -1.24 -2.46
N59721 SERPINE2 Plasminogen activator inhibitor type 1 member 2 -1.38 -2.87
Motility and cytoskeleton
CR936693 ADD1 Adducin 1 (alpha) -3.93 -4.66
N49912 ARHGDIB Rho GDP dissociation inhibitor beta -2.41 -6.07
AA009697 CDC42 Cell division cycle 42 2.03 1.73
AA148200 ILK Integrin-linked kinase-2 2.09 1.66
Signal transduction
AI140863 EDN2 Endothelin 2 3.12 1.10
AA446994 FGFR4 Fibroblast growth factor receptor 4 -1.17 -2.06
N20338 HGS Hepatocyte growth factor-regulated tyrosine kinase substrate 2.16 1.53
AA026831 KDR Kinase insert domain receptor 3.33 1.09
W55872 NFKBIA NFKB inhibitor, alpha 2.25 1.66
H26426 PTPRM PTP, receptor M 1.23 -2.05
H07991 VEGFC Vascular endothelial growth factor C 2.20 2.61
Transcription related
H21041 ATF3 Activating transcription factor 3 2.31 1.65
AA026120 BHLHB2 Basic helix-loop-helix domain containing class B2 1.04 -2.11
AA868008 HIST1H4C Histone 1, H4c 2.50 2.15
Cell Cycle and apoptosis
AA489752 CCNG2 Cyclin G2 2.18 -1.73
AA486628 EGR1 Early growth response 1 4.20 1.53
N94468 JUNB Homo sapiens jun B proto-oncogene 2.05 1.04
AA826373 RRM2 Ribonucleotide reductase M2 3.30 5.53
AA039640 WEE1 WEE1 homolog 4.78 2.24
Cytokines and immune response
W46900 CXCL1 Chemokine (C-X-C motif) ligand 1 3.56 2.58
N31850 IL24 Interleukin 24 2.88 -2.16
  1. Genes are grouped by function and arranged by alphabetic order. Genes differentially expressed with statistically significance (FDR < 0.15) between E-cadherin and P-cadherin are highlighted in bold letter. Mean E-cadh: mean gene expression value in two E-cadherin clones; Mean P-cadh: mean gene expression value in two P-cadherin clones. Negative value indicates that gene expression is down-regulated with respect to control cells.