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Table 2 Selection of genes modulated at least 2 fold after E-cadherin and/or P-cadherin induction with respect to control cells.

From: Functional characterization of E- and P-cadherin in invasive breast cancer cells

GenBank accession #

Gene Symbol

Description

Mean E-cadh

Mean P-cadh

Cellular adhesion and Extracellular Matrix

AA865745

CDH18

Cadherin 18, type 2

2.07

1.09

AI003692

CDH4

Cadherin 4, R-cadherin (retinal)

2.03

-1.20

H11732

CLECSF2

C-type lectin domain 2, member B

4.45

3.86

AA478481

COL12A1

Collagen, type XII, alpha 1

2.90

2.01

AW467461

ITGB2

Integrin beta 2

-2.28

-1.98

N33214

MMP14

Matrix metalloproteinase 14

-1.24

-2.46

N59721

SERPINE2

Plasminogen activator inhibitor type 1 member 2

-1.38

-2.87

Motility and cytoskeleton

CR936693

ADD1

Adducin 1 (alpha)

-3.93

-4.66

N49912

ARHGDIB

Rho GDP dissociation inhibitor beta

-2.41

-6.07

AA009697

CDC42

Cell division cycle 42

2.03

1.73

AA148200

ILK

Integrin-linked kinase-2

2.09

1.66

Signal transduction

AI140863

EDN2

Endothelin 2

3.12

1.10

AA446994

FGFR4

Fibroblast growth factor receptor 4

-1.17

-2.06

N20338

HGS

Hepatocyte growth factor-regulated tyrosine kinase substrate

2.16

1.53

AA026831

KDR

Kinase insert domain receptor

3.33

1.09

W55872

NFKBIA

NFKB inhibitor, alpha

2.25

1.66

H26426

PTPRM

PTP, receptor M

1.23

-2.05

H07991

VEGFC

Vascular endothelial growth factor C

2.20

2.61

Transcription related

H21041

ATF3

Activating transcription factor 3

2.31

1.65

AA026120

BHLHB2

Basic helix-loop-helix domain containing class B2

1.04

-2.11

AA868008

HIST1H4C

Histone 1, H4c

2.50

2.15

Cell Cycle and apoptosis

AA489752

CCNG2

Cyclin G2

2.18

-1.73

AA486628

EGR1

Early growth response 1

4.20

1.53

N94468

JUNB

Homo sapiens jun B proto-oncogene

2.05

1.04

AA826373

RRM2

Ribonucleotide reductase M2

3.30

5.53

AA039640

WEE1

WEE1 homolog

4.78

2.24

Cytokines and immune response

W46900

CXCL1

Chemokine (C-X-C motif) ligand 1

3.56

2.58

N31850

IL24

Interleukin 24

2.88

-2.16

  1. Genes are grouped by function and arranged by alphabetic order. Genes differentially expressed with statistically significance (FDR < 0.15) between E-cadherin and P-cadherin are highlighted in bold letter. Mean E-cadh: mean gene expression value in two E-cadherin clones; Mean P-cadh: mean gene expression value in two P-cadherin clones. Negative value indicates that gene expression is down-regulated with respect to control cells.