From: Carboxypeptidase 4 gene variants and early-onset intermediate-to-high risk prostate cancer
SNP | Genotype | Cases, n (%) | Controls, n (%) | Odds Ratio (95% CI)* | p-value |
---|---|---|---|---|---|
rs901799 | CC | 363 (71.7) | 372 (73.5) | 1 | |
CA | 131 (2.6) | 121(23.9) | 1.11 (0.83 – 1.48) | 0.46 | |
AA | 12 (2.4) | 13 (2.6) | 0.95 (0.43 – 2.1) | 0.90 | |
rs3807344 | AA | 213 (42.1) | 201 (39.7) | 1 | |
AG | 221 (43.7) | 244 (48.2) | 0.85 (0.66 – 1.11) | 0.25 | |
GG | 72 (14.2) | 61 (12.1) | 1.11 (0.75 – 1.65) | 0.59 | |
rs1569132 | AA | 172 (34.0) | 165 (32.6) | 1 | |
AG | 234 (46.2) | 252 (49.8) | 0.89 (0.67 – 1.18) | 0.41 | |
GG | 100 (19.8) | 89 (17.6) | 1.08 (0.75 – 1.54) | 0.68 | |
rs1038628 | GG | 209 (41.3) | 212 (41.9) | 1 | |
GT | 220 (43.5) | 221 (43.7) | 1.01 (0.77 – 1.33) | 0.94 | |
TT | 77 (15.2) | 73 (14.4) | 1.07 (0.73 – 1.57) | 0.78 | |
rs2171492 | GG | 216 (42.7) | 212 (41.9) | 1 | |
GT | 216 (42.7) | 233 (46.0) | 0.91 (0.7 – 1.19) | 0.49 | |
TT | 74 (14.6) | 61 (12.1) | 1.19 (0.8 – 1.77) | 0.38 | |
rs1488009 | AA | 402 (79.4) | 387(76.5) | 1 | |
AG | 93 (18.4) | 114 (22.5) | 0.78 (0.57 – 1.07) | 0.12 | |
GG | 11 (2.2) | 5 (0.01) | 2.12 (0.73 – 6.16) | 0.17 |