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Table 3 Grade 3 or 4 drug related adverse events

From: Randomised Phase I/II trial assessing the safety and efficacy of radiolabelled anti-carcinoembryonic antigen I131KAb201 antibodies given intra-arterially or intravenously in patients with unresectable pancreatic adenocarcinoma

Event

Intra-arterial

(n = 9)

Intra-venous

(n = 9)

Total

(n = 18)

Lymphopenia

3

2

5

Thrombocytopenia

4

2

6

Leukopenia

4

0

4

Neutropenia

3

0

3

Sepsis

1

1

2

Vomiting

1

1

2

Alanine aminotransferase

1

0

1

Anaemia

0

1

1

Anorexia

0

1

1

Aspartate aminotransferase

1

0

1

Blood alkaline phosphatase

1

0

1

Febrile neutropenia

1

0

1

Haematemesis

0

1

1

Neutrophilia

1

0

1

Thrombosis

1

0

1