BRCA1 | BRCA2 | BRCA1+2 | Total | |
---|---|---|---|---|
a: Prevalence of the MDM2 SNP309 subtypes in BRCA mutation carriers | ||||
Homozygotes G-G | 29(26.1)% | 16(23%) | 45(25%) | |
Hetrozygotes | 55(49.5%) | 39(57.3%) | 94(52.2%) | |
Homozygotes T-T | 27(24.3%) | 13(19.1%) | 1(100%) | 41(22.7%) |
Total | 111 | 68 | 1 | 180 |
b: Prevalence of the MDM2 SNP309 subtypes in the overall population | ||||
BRCA Carriers | Non Carriers | |||
Frequency | Percent | Frequency | Percent | |
Homozygotes G-G | 45 | 25.00% | 68 | 25.00% |
Hetrozygotes | 94 | 52.20% | 139 | 51.10% |
Homozygotes T-T | 41 | 22.80% | 65 | 23.90% |
Total | 180 | 272 |