Table 3 Comparison of gene amplification analysis and immunohistochemical results of HER-2/neu in 47 cases of ESCC
IHC c-erbB-2 | FISH HER-2 | |||
|---|---|---|---|---|
| Â | Not Amplified (%) | Polysomy 17 (%) | Amplified (%) | Total |
0/1+ | 10 (30.3) | 1 (20) | 0 (0) | 11 |
2+ | 13 (39.4) | 2 (40) | 0 (0) | 15 |
3+ | 4 (12.1) | 2 (40) | 6 (66.7) | 12 |
NA | 6 (18.2) | 0 (0) | 3 (33.3) | 9 |
Total | 33 (100) | 5 (100) | 9 (100) | 47 |