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Table 3 Comparison of gene amplification analysis and immunohistochemical results of HER-2/neu in 47 cases of ESCC

From: Evaluation of gene amplification and protein expression of HER-2/neu in esophageal squamous cell carcinoma using Fluorescence in situ Hybridization (FISH) and immunohistochemistry

IHC
c-erbB-2
FISH HER-2
  Not Amplified (%) Polysomy 17 (%) Amplified (%) Total
0/1+ 10 (30.3) 1 (20) 0 (0) 11
2+ 13 (39.4) 2 (40) 0 (0) 15
3+ 4 (12.1) 2 (40) 6 (66.7) 12
NA 6 (18.2) 0 (0) 3 (33.3) 9
Total 33 (100) 5 (100) 9 (100) 47
  1. NA: not available