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Table 1 Clinicopathological findings of ESCC cases selected for this study

From: Evaluation of gene amplification and protein expression of HER-2/neu in esophageal squamous cell carcinoma using Fluorescence in situ Hybridization (FISH) and immunohistochemistry

Variable

Category

N (%)

Total

Gender

Male

161 (80.9)

199

 

Female

38 (19.1)

 

Ethnicity

Caucasian

148 (74.4)

199

 

Not Caucasian

42 (21.1)

 
 

No data available

9 (4.5)

 

Tumor location

Upper

34 (17.1)

199

 

Middle

104 (52.3)

 
 

Lower

50 (25.1)

 
 

No data available

11 (5.5)

 

Histological grade

G1

62 (31.2)

199

 

G2

93 (46.7)

 
 

G3

42 (21.1)

 
 

G4

2 (1)

 

Infiltration level

Basal layer

9 (4.5)

199

 

Muscular

42 (21.1)

 
 

Adventitia

148 (74.4)

 

Lymphatic invasion

Not observed

160 (80.4)

199

 

Present

39 (19.6)

 

Venous invasion

Not observed

58 (29.1)

199

 

Present

141 (70.9)

 

pN

Negative

107 (53.8)

199

 

Positive

89 (44.7)

 
 

No data available

3 (1.5)

 

Surgical margins

Not committed

6 (3.0)

199

 

Committed

188 (94.5)

 
 

No data available

5 (2.5)

 

Stage

I

6 (3)

199

 

II

86 (43.2)

 
 

III

53 (26.6)

 
 

IV

52 (26.1)

 
 

No data available

2 (1)

 

Tumor recurrence

Negative

87 (43.7)

199

 

Positive

110 (55.3)

 
 

No data available

2 (1)

 

Evolution of disease

Death from disease

153 (76,9)

199

 

Alive without disease

7 (3.5)

 
 

Alive with disease

1 (0.5)

 
 

No follow-up

38 (19.1)

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