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Table 1 Clinicopathological findings of ESCC cases selected for this study

From: Evaluation of gene amplification and protein expression of HER-2/neu in esophageal squamous cell carcinoma using Fluorescence in situ Hybridization (FISH) and immunohistochemistry

Variable Category N (%) Total
Gender Male 161 (80.9) 199
  Female 38 (19.1)  
Ethnicity Caucasian 148 (74.4) 199
  Not Caucasian 42 (21.1)  
  No data available 9 (4.5)  
Tumor location Upper 34 (17.1) 199
  Middle 104 (52.3)  
  Lower 50 (25.1)  
  No data available 11 (5.5)  
Histological grade G1 62 (31.2) 199
  G2 93 (46.7)  
  G3 42 (21.1)  
  G4 2 (1)  
Infiltration level Basal layer 9 (4.5) 199
  Muscular 42 (21.1)  
  Adventitia 148 (74.4)  
Lymphatic invasion Not observed 160 (80.4) 199
  Present 39 (19.6)  
Venous invasion Not observed 58 (29.1) 199
  Present 141 (70.9)  
pN Negative 107 (53.8) 199
  Positive 89 (44.7)  
  No data available 3 (1.5)  
Surgical margins Not committed 6 (3.0) 199
  Committed 188 (94.5)  
  No data available 5 (2.5)  
Stage I 6 (3) 199
  II 86 (43.2)  
  III 53 (26.6)  
  IV 52 (26.1)  
  No data available 2 (1)  
Tumor recurrence Negative 87 (43.7) 199
  Positive 110 (55.3)  
  No data available 2 (1)  
Evolution of disease Death from disease 153 (76,9) 199
  Alive without disease 7 (3.5)  
  Alive with disease 1 (0.5)  
  No follow-up 38 (19.1)