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Table 2 Association of polySia-NCAM and NCAM expression of untreated primary neuroblastomas with histological variables.

From: Absence of polysialylated NCAM is an unfavorable prognostic phenotype for advanced stage neuroblastoma

Variable

PolySia-NCAM-positive (17)

PolySia-NCAM-negative (14)

P value

NCAM positive (20)

NCAM negative (11)

P value

INPC (30*)

 

*

0.623

 

*

0.165

Undifferentiated (12)

8

4

 

10

2

 

Poorly differentiated (6)

4

2

 

5

1

 

Differentiating (9)

4

5

 

4

5

 

Ganglioneuroblastoma (2)

1

1

 

1

1

 

Ganglioneuroma (1)

 

1

  

1

 

MEAN PI (31)

36.0 ± 17.6

19.9 ± 14.7

0.011

36.1 ± 16.6

15.3 ± 12.3

0.001

MYCN (31)

  

0.316

  

0.183

nonamplified (24)

12

12

 

14

10

 

amplified (7)

5

2

 

6

1

 
  1. Number of patients in each group is shown in parenthesis. P-values are measured for differences between categorical variables (polySia-NCAM or NCAM expression status). *An intracranial neuroblastoma was excluded from the INPC classification. Abbreviations: INPC = International Neuroblastoma Pathology Classification; PI = proliferation index.
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BMC Cancer

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