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Table 2 Association of polySia-NCAM and NCAM expression of untreated primary neuroblastomas with histological variables.

From: Absence of polysialylated NCAM is an unfavorable prognostic phenotype for advanced stage neuroblastoma

Variable PolySia-NCAM-positive (17) PolySia-NCAM-negative (14) P value NCAM positive (20) NCAM negative (11) P value
INPC (30*)   * 0.623   * 0.165
Undifferentiated (12) 8 4   10 2  
Poorly differentiated (6) 4 2   5 1  
Differentiating (9) 4 5   4 5  
Ganglioneuroblastoma (2) 1 1   1 1  
Ganglioneuroma (1)   1    1  
MEAN PI (31) 36.0 ± 17.6 19.9 ± 14.7 0.011 36.1 ± 16.6 15.3 ± 12.3 0.001
MYCN (31)    0.316    0.183
nonamplified (24) 12 12   14 10  
amplified (7) 5 2   6 1  
  1. Number of patients in each group is shown in parenthesis. P-values are measured for differences between categorical variables (polySia-NCAM or NCAM expression status). *An intracranial neuroblastoma was excluded from the INPC classification. Abbreviations: INPC = International Neuroblastoma Pathology Classification; PI = proliferation index.