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Table 1 Association of polySia-NCAM and NCAM expression of untreated primary neuroblastomas with clinical variables.

From: Absence of polysialylated NCAM is an unfavorable prognostic phenotype for advanced stage neuroblastoma

Variable

PolySia-NCAM-positive (17)

PolySia-NCAM-negative (14)

P value

NCAM positive (20)

NCAM negative (11)

P value

MEAN AGE (31)

2.9 ± 3.3

4.6 ± 5.0

0.258

3.4 ± 3.9

4.1 ± 4.7

0.683

AGE (31)

  

0.613

  

0.890

< 1.0 year (8)

5

3

 

5

3

 

> 1.0 year (23)

12

11

 

15

8

 
   

0.465

  

0.939

< 1.5 yrs (11)

7

4

 

7

4

 

> 1.5 yrs (20)

10

10

 

13

7

 

CLINICAL STAGE (31)

  

0.047

  

0.053

LD, extirpation (7)

1

6

 

2

5

 

LD with RLNI (4)

3

1

 

3

1

 

Distant metastases (19)

13

6

 

15

4

 

INSS 4S (1)

0

1

  

1

 
  1. Number of patients in each variable group is shown in parenthesis. P-values are measured for differences between categorical variables (polySia-NCAM or NCAM expression status). Abbreviations: LD = local disease; RLNI = regional lymph node involvement; BM = bone marrow; INSS = International Neuroblastoma Staging System