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Table 2 Summary of LOH analysis of FATgene locus in astrocytic tumors (20 grade II and 20 grade IV) with microsatellite markers.

From: Frequent loss of heterozygosity and altered expression of the candidate tumor suppressor gene 'FAT' in human astrocytic tumors

Microsatellite markers D4S

 

D4S3173

D4S2827

D4S1295

D4S2643

D4S2672

Informative samples

Grade II

U

U

6/20 (30%)

U

U

 

Grade IV

U

U

5/20 (25%)

U

U

LOH per informative samples

Grade II

U

U

3/6 (50%)

U

U

 

Grade IV

U

U

2/5 (40%)

U

U

Total LOH per informative samples

(Grade II & IV)

 

U

U

5/11 (45.45%)

U

U

  1. Only one marker (D4S1295) was informative, other 4 markers were uninformative (U).