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Table 4 Risk assessment among different loci of HLA class I

From: High resolution human leukocyte antigen (HLA) class I and class II allele typing in Mexican mestizo women with sporadic breast cancer: case-control study

 

CASES

N = 174

CONTROLS

N = 186

   

Locus

n

g.f

n

g.f

P

OR

C195%

HLA-A

       

0201

39

0.224

41

0.220

0.96

1.022

0.621–1.68

2402

25

0.143

31

0.166

0.648

0.839

0.473–1.48

0206

20

0.114

10

0.053

0.056

2.286

1.038–5.033*

3101

16

0.091

13

0.069

0.565

1.348

0.628–2.890

6801

8

0.045

19

0.102

0.068

0.424

0.180–0.995

HAL-B

       

1501

13

0.075

4

0.021

0.031

3.714

1.187–11.619+

3501

13

0.075

11

0.059

0.704

1.285

0.560–2.949

4002

11

0.063

13

0.069

0.966

0.898

0.391–2.062

5101

9

0.052

11

0.059

0.939

0.868

0.351–2.148

5201

9

0.052

4

0.021

0.21

2.482

0.750–8.211

HLA-Cw

       

0401

34

0.195

36

0.194

0.929

1.012

0.6–1.706

0702

29

0.167

40

0.215

0.302

0.73

0.430–1.241

0102

16

0.092

15

0.081

0.846

1.154

0.553–2.412

0701

13

0.075

9

0.048

0.411

1.588

0.661–3.814

0602

11

0.063

8

0.043

0.535

1.502

0.589–3.825

  1. * Pc = 0.45. +Pc = 0.30.