Figure 5
From: Restoration of contact inhibition in human glioblastoma cell lines after MIF knockdown
Blocking MIF with a monoclonal antibody decreases proliferation of glioblastoma cell lines at high cell density. The human glioblastoma cell lines LN18 (A) and LN229 (B) were incubated with a monoclonal MIF antibody (6F12) for 6 h. Measurement of DNA synthesis at low and high cell densities revealed a significant reduction of proliferation at high density (* p < 0.05, n.s. not significant).