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Table 1 H3K27me3 expression and clinicopathologic variables (Chi-square test)

From: Prognostic impact of H3K27me3 expression on locoregional progression after chemoradiotherapy in esophageal squamous cell carcinoma

  

H3K27me3 expression (%)

 

Variables

Case

low

high

P

Age (years)

   

0.255

   ≤55a

54

32(59.3)

22(40.7)

 

   >55

44

21(47.7)

23(52.3)

 

Gender

   

0.720

   Male

82

45(54.9)

37(45.1)

 

   Female

16

8(50.0)

8(50.0)

 

Location

   

0.341

   Cervical

24

15(62.5)

9(37.5)

 

   Thoracic

74

38(51.4)

36(48.6)

 

WHO grade

   

0.016

   G1

24

16(66.7)

8(33.3)

 

   G2

50

30(60.0)

20(40.0)

 

   G3-4

24

7(29.2)

17(70.8)

 

Tumor size (cm)

   

0.019

   ≤6b

56

36(64.3)

20(35.7)

 

   >6

42

17(40.5)

25(59.5)

 

T status

   

0.024

   T2-3

47

31(66.0)

16(34.0)

 

   T4

51

22(43.1)

29(56.9)

 

N status

   

0.929

   N0

16

8(50.0)

8(50.0)

 

   N1

82

40(48.8)

42(51.2)

 

M status

   

0.651

   M0

59

33(55.9)

26(44.1)

 

   M1-lymc

39

20(51.3)

19(48.7)

 

CRT response

   

0.094

   Effective

61

37(60.7)

24(39.3)

 

   Resistant

37

16(43.2)

21(56.8)

 

Locoregional progression

   

0.009

   Absent

51

34(66.7)

17(33.3)

 

   Present

47

19(40.4)

28(59.6)

 

Distant progression

   

0.299

   Absent

62

36(58.1)

26(41.9)

 

   Present

36

17(47.2)

19(52.8)

 
  1. aMean age. bMean tumor size. cDistant lymph node metastasis.