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Table 1 H3K27me3 expression and clinicopathologic variables (Chi-square test)
| H3K27me3 expression (%) | ||||
|---|---|---|---|---|
| Variables | Case | low | high | P |
| Age (years) | 0.255 | |||
| ≤55a | 54 | 32(59.3) | 22(40.7) | |
| >55 | 44 | 21(47.7) | 23(52.3) | |
| Gender | 0.720 | |||
| Male | 82 | 45(54.9) | 37(45.1) | |
| Female | 16 | 8(50.0) | 8(50.0) | |
| Location | 0.341 | |||
| Cervical | 24 | 15(62.5) | 9(37.5) | |
| Thoracic | 74 | 38(51.4) | 36(48.6) | |
| WHO grade | 0.016 | |||
| G1 | 24 | 16(66.7) | 8(33.3) | |
| G2 | 50 | 30(60.0) | 20(40.0) | |
| G3-4 | 24 | 7(29.2) | 17(70.8) | |
| Tumor size (cm) | 0.019 | |||
| ≤6b | 56 | 36(64.3) | 20(35.7) | |
| >6 | 42 | 17(40.5) | 25(59.5) | |
| T status | 0.024 | |||
| T2-3 | 47 | 31(66.0) | 16(34.0) | |
| T4 | 51 | 22(43.1) | 29(56.9) | |
| N status | 0.929 | |||
| N0 | 16 | 8(50.0) | 8(50.0) | |
| N1 | 82 | 40(48.8) | 42(51.2) | |
| M status | 0.651 | |||
| M0 | 59 | 33(55.9) | 26(44.1) | |
| M1-lymc | 39 | 20(51.3) | 19(48.7) | |
| CRT response | 0.094 | |||
| Effective | 61 | 37(60.7) | 24(39.3) | |
| Resistant | 37 | 16(43.2) | 21(56.8) | |
| Locoregional progression | 0.009 | |||
| Absent | 51 | 34(66.7) | 17(33.3) | |
| Present | 47 | 19(40.4) | 28(59.6) | |
| Distant progression | 0.299 | |||
| Absent | 62 | 36(58.1) | 26(41.9) | |
| Present | 36 | 17(47.2) | 19(52.8) | |
