Table 1 Patient's data and correlation between levels of mtDNA in peripheral blood of patients with breast cancer and clinical-pathological parameters
From: Decreased mitochondrial DNA content in blood samples of patients with stage I breast cancer
Variable | Number | mtDNA content Median (Range) | P value |
|---|---|---|---|
Age (years) | Â | Â | Â |
   <50 | 30 | 525.96 (0.47 - 35241.80) | *0.564 |
   ≥50 | 30 | 660.59 (0.39 - 27175.14) |  |
Menopausal status | Â | Â | Â |
   pre | 37 | 1365.30 (0.47 - 35241.80) | *0.024 |
   post | 23 | 262.29 (0.39 - 5166.60) |  |
Lymph-node status | Â | Â | Â |
   negative | 29 | 668.60 (4.23 - 27175.14) | *0.673 |
   positive | 31 | 436.55 (0.39 - 35241.80) |  |
Stage | Â | Â | Â |
   I | 20 | 196.94 (0.47 - 6841.04) | **0.023 |
   II | 20 | 1656.18 (10.89 - 35241.80) |  |
   III-IV | 20 | 572.71 (0.39 - 4956.14) |  |
ER | Â | Â | Â |
   positive | 29 | 657.11 (0.39 - 35241.80) | *0.877 |
   negative | 31 | 376.11 (0.47 - 27175.14) |  |
PR | Â | Â | Â |
   positive | 36 | 654.85 (4.23 - 27175.14) | *0.763 |
   negative | 24 | 669.09 (0.39 - 35241.80) |  |
Her2/neu protein | Â | Â | Â |
   positive | 32 | 242.96 (0.39 - 35241.80) | *0.335 |
   negative | 28 | 824.78 (10.89 - 27175.14) |  |