Differential gene expression between Gleason 3 and Gleason 4 transcriptomes. A: Expression levels of selected genes in G3 and G4 relative to luminal cells. B: Expression levels of these G3 and G4 genes in G3+4 vs. G4+5 tumors. C: Differential expression of epithelial genes in G3 and G4 relative to luminal cells. D: Display for LNCaP genes in primary tumors. Positive log2(Cancer/Normal) on the y-axis indicates increased cancer expression and negative log2 indicates decreased cancer expression.