Table 2 Uptake of [³H]-5-fluorouracil (5FU), interstitial fluid pressure (P_if), collagen content and malondialdehyd (MDA) levels in controls and after repeated or single hyperbaric oxygen exposure (HBO).

Uptake of [ ³ H]-5FU

(AUC tumor/AUC plasma)

0.17 ± 0.12

(n = 7)

0.20 ± 0.11

(n = 8)

0.42 ± 0.21 *

(n = 5)

P _if

(mmHg)

5.5 ± 2.6

(n = 9)

2.3 ± 2.7*

(n = 11)

2.5 ± 2.9*

(n = 17)

%collagen of dry weight

11.6 ± 5.0

(n = 6)

5.0 ± 1.1*

(n = 4)

MDA levels

(nmol/mg prot)

0.09 ± 0.01

(n = 5)

0.15 ± 0.11

(n = 5)

0.09 ± 0.02

(n = 5)