Table 3 Genetic polymorphisms in combination of ERCC1 and XRCC1 and survival of patients

all

0 variant

67(26.1)

25.10

1.00

1 variant allele

100(38.9)

13.07

1.52(1.04-2.22)

2 variant alleles

58(22.6)

9.27

< 0.001

2.33(1.54-3.50)

3 variant alleles

26(10.1)

6.30

2.98(1.76-5.04)

4 variant alleles

6(2.3)

3.87

9.24(3.50-24.44)

I and II

0 variant

26(33.3)

45.80

1.00

1 variant allele

30(38.5)

22.27

1.98(0.86-4.58)

2 variant alleles

14(17.9)

11.60

0.145

2.81(1.10-7.13)

3 variant alleles

6(7.7)

--^b

1.41(0.26-6.75)

4 variant alleles

2 (2.6)

17.27

9.05(1.04-78.76)

III and IV

0 variant

41(22.9)

19.10

1.00

1 variant allele

70(39.1)

11.17

1.54(0.98-2.39)

2 variant alleles

44(24.6)

8.93

< 0.001

2.29(1.44-3.66)

3 variant alleles

20(11.2)

5.83

3.69(2.06-6.62)

4 variant alleles

4(2.2)

3.63

18.50(5.68-60.23)