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Table 2 Significance of the NTRK1 genotypes of MAF>5% and clinical and biological features of the disease on long-time OS rates assessed by multivariate Cox hazard regression model (overall significance of the model at p = 0.00016).

From: c.1810C>T Polymorphism of NTRK1Gene is associated with reduced Survival in Neuroblastoma Patients

Feature HR 95%CI p value (Wald statistics)
   Age ≤18 months 0.22 0.07-0.70 p = 0.010
   MYCN amplification 3.47 1.11-10.8 p = 0.032
   NTRK1 c.1810T allele 4.54 1.07-19.3 p = 0.041
   unfavorable histology 3.01 0.67-13.4 p = 0.149
   chromosome 1 p deletion/imbalance 1.44 0.46-4.46 p = 0.531
   NTRK1 c.1887T allele 0.69 0.15-2.99 p = 0.619
   NTRK1 c.1674A allele 1.21 0.43-3.43 p = 0.714
   Stage 4 1.15 0.42-3.14 p = 0.789
  1. HR - hazard ratio; CI - confidence intervals