Table 2 Significance of the NTRK1 genotypes of MAF>5% and clinical and biological features of the disease on long-time OS rates assessed by multivariate Cox hazard regression model (overall significance of the model at p = 0.00016).

   Age ≤18 months

0.22

0.07-0.70

p = 0.010

   MYCN amplification

3.47

1.11-10.8

p = 0.032

   NTRK1 c.1810T allele

4.54

1.07-19.3

p = 0.041

   unfavorable histology

3.01

0.67-13.4

p = 0.149

   chromosome 1 p deletion/imbalance

1.44

0.46-4.46

p = 0.531

   NTRK1 c.1887T allele

0.69

0.15-2.99

p = 0.619

   NTRK1 c.1674A allele

1.21

0.43-3.43

p = 0.714

   Stage 4

1.15

0.42-3.14

p = 0.789