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Figure 1 | BMC Cancer

Figure 1

From: c.1810C>T Polymorphism of NTRK1Gene is associated with reduced Survival in Neuroblastoma Patients

Figure 1

Sequence variants of the NTRK1 gene identified in the present study. The structure of TrkA receptor. Extracellular part of the protein consists of: two cysteine clusters (Cys); three leucine-rich motifs (LRM) and two immunoglobulin-like C2 domains (Ig-C2). It is followed by a short transmembrane portion (TM), and intracellular juxtamembrane domain (JM) and tyrosine kinase domain (TK). * - newly identified sequence variants, circled - the SNPs having MAF (minor allele frequency) value >5%, arrows - exonic localization of the variants, dishes - intronic localization of the variants.

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