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Table 1 Association between HIF-1α and clinicopathological factors

From: Expression of HIF-1alpha and VEGF in colorectal cancer: association with clinical outcomes and prognostic implications

Factors No. of patients HIF-1α  
   Positive expression χ2 P
Age     
<60 24 15(62.5%) 0.839 0.363
≥ 60 47 24(51.1%)   
Sex     
Male 43 24(55.8%) 0.034 0.853
Female 28 15(53.6%)   
Tumor size     
<5 cm 31 17(54.8%) 0.000 0.989
≥ 5 cm 40 22(55%)   
Differentiation
grade
    
Poor 11 4(36.4%) 2.233 0.327
Moderate 48 27(56.3%)   
Well 12 8(66.7%)   
Invasion Depth     
T1 + T2 10 6(60%) 0.121 0.728
T3 + T4 61 33(54.1%)   
Tumor stage     
I+II 42 15(35.7%) 15.336 <0.001
III+IV 29 24(82.8%)   
lymphnode matastasis,     
No 44 17(38.6%) 12.007 <0.001
Yes 27 22(81.5%)   
liver matastasis     
NO 60 29(48.3%) 6.806 0.009
Yes 11 10(90.1%)