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Table 1 Relationship between CRC clinicopathologic features and ST6Gal I activity

From: Synthesis and expression of CDw75 antigen in human colorectal cancer

ST6Gal Activity
  Tumor p Tumor/Healthy p Net increase p n
  Means ± SEM   Means ± SEM   Means ± SEM   
Age (years)        
< 69 61.89 ± 13.17 0.887 2.21 ± 0.52 0.981 54.52 ± 12.25 0.042 9
69-77 58.85 ± 15.18   4.25 ± 1.99   62.25 ± 21.74   9
> 77 38.48 ± 6.75   2.60 ± 0.89   20.23 ± 6.04   10
Tumour location        
Proximal 41.36 ± 9.28 0.231 2.21 ± 0.87 0.442 28.09 ± 10.11 0.308 7
Distal 72.12 ± 12.58   3.54 ± 1.35   63.46 ± 14.78   13
Rectum 34.56 ± 8.03   2.01 ± 0.69   25.99 ± 9.26   7
Size (cm)        
<4 69.89 ± 18.74 0.130 4.96 ± 2.28 0.033 56.86 ± 20.75 0.727 9
4-5 41.45 ± 9.07   1.49 ± 0.320   37.00 ± 13.83   9
> 5 55.81 ± 8.42   3.60 ± 1.17   38.47 ± 6.35   9
Histologic type        
Poorly differentiated 8.27 0.208 1.49 0.371 2.72 0.156 1
Moderately differentiated 57.66 ± 7.63   3.27 ± 0.80   49.01 ± 8.99   24
Well differentiated 25.34 ± 0.98   0.80 ± 0.28   2.16   1
Growth type        
Polypoid 47.28 ± 10.13 0.915 1.83 ± 0.39 0.414 36.93 ± 11.41 0.716 12
Non polypoid 34.31 ± 11.21   2.75 ± 1.16   23.24 ± 11.56   4
TNM classification        
T        
T1/T2 76.09 ± 30.13 0.223 3.68 ± 2.25 0.510 74.94 ± 38.60 0.421 3
T3 54.12 ± 8.08   3.12 ± 0.87   43.97 ± 9.65   33
T4 29.00 ± 9.49   1.33 ± 0.58   22.63 ± 19.91   4
N        
N0 59.90 ± 10.26 0.139 3.27 ± 1.08 0.443 47.34 ± 11.58 0.491 24
N1 55.83 ± 14.00   3.53 ± 1.50   51.26 ± 16.17   9
N2 27.19 ± 6.90   1.26 ± 0.33   18.07 ± 12.27   7
M        
M0 55.76 ± 7.60 0.616 3.16 ± 0.79 0.254 46.42 ± 8.92 - 37
M1 24.93   0.62   -   1
AJCC classification        
I 76.09 ± 30.13 0.146 3.68 ± 2.25 0.597 74.94 ± 38.60 0.407 3
IIa 60.05 ± 11.39   3.30 ± 1.27   46.63 ± 12.82   20
IIb 13.17 ± 4.90   0.89 ± 0.59   2.72   2
IIIb 59.70 ± 15.26   3.89 ± 1.66   51.26 ± 16.17   8
IIIc 28.72 ± 7.96   1.42 ± 0.34   18.07 ± 12.27   6
IV -   0.62   -   1
  1. Relationship between CRC patient's clinicopathologic features and tumour stading and ST6Gal I activity. Tumour/Healthy represents the quotient of the enzyme activity from the two tissues of the same patient. Net increase represents the difference of the enzyme activity from tumour and healthy tissues from the same patient. The ST6Gal I activity and the net increase are expressed as μU/mg protein. Data are represented as means ± SEM (standard error of the means) of the n patients analyzed. p was obtained from the Mann-Whitney U test (for tumour growth type) and Kruskall-Wallis test (for the rest of variables).