Expression of HIWI in human esophageal squamous cell carcinoma is significantly associated with poorer prognosis

BMC Cancer

Table 1 Clinicopathological features and HIWI expression in esophageal squamous cell carcinoma

Parameters	Cases (%)	Cytoplasma			Nucleus				Cytoplasma and Nucleus
		Low	High	P	Low	High	P	Low	Moderate	High	P
Age				0.683			0.830				0.727
<51	48 (31.4)	21	27		31	17		13	26	9
51-60	52 (34.0)	25	27		36	16		19	23	10
>60	53 (34.6)	21	32		37	16		14	30	9
Gender				0.448			0.666				0.251
Male	93 (60.8)	43	50		62	31		31	43	19
Female	60 (39.2)	24	36		42	18		15	36	9
Location				0.813			0.311				0.556
Upper	14 (9.2)	5	9		7	7		3	6	5
Middle	101 (66.0)	44	57		71	30		31	53	17
Lower	35 (22.9)	16	19		24	11		11	18	6
Missing	3 (2.0)	2	1		2	1		1	2	0
Size				0.778			0.881				0.705
<31 mm	25 (16.3)	11	14		18	7		7	15	3
31-60 mm	105 (68.6)	48	57		73	32		34	53	18
>60 mm	14 (9.2)	5	9		9	5		4	6	4
Missing	9 (5.9)	3	6		4	5		1	5	3
Lymph node metastasis				0.904			0.232				0.593
-	99 (64.7)	43	56		64	35		27	53	19
+	54 (35.3)	24	30		40	14		19	26	9
UICC stage				0.074			0.148				0.662
I	0	0	0		0	0		0	0	0
II	100 (65.4)	49	51		64	36		32	49	19
III	53 (34.6)	18	35		40	13		14	30	9
IV	0	0	0		0	0		0	0	0
T stage				0.035*			0.278				0.002*
I	5 (3.3)	4	1		4	1		3	2	0
II	39 (25.5)	23	16		31	8		19	16	4
III	100 (65.4)	37	63		63	37		24	52	24
IV	9 (5.9)	3	6		6	3		0	9
Histological grade				0.011*			0.352				0.126
Well	53 (34.6)	31	22		37	16		21	26	6
Moderate	60 (39.2)	25	35		37	23		17	28	15
Poor	40 (26.1)	11	29		30	10		8	25	7
Patients at follow-up				<0.001*			0.981				0.001*
Alive	56 (36.6)	35	21		38	18		27	19	10
Dead	97 (63.4)	32	65		66	31		19	60	18

ISSN: 1471-2407