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Figure 2 | BMC Cancer

Figure 2

From: Identification of colorectal cancer patients with tumors carrying the TP53mutation on the codon 72 proline allele that benefited most from 5-fluorouracil (5-FU) based postoperative chemotherapy

Figure 2

Effect of chemotherapy and the TP53 mutation in colorectal cancer patients of Dukes' stage C. (a): Overall survival of Dukes' stage C patients with the TP53 mutation and without the mutation (n = 62, P = 0.891). (b): Overall survival of patients with surgical treatment alone and with postoperative chemotherapy (n = 62, P = 0.037). Patients at Dukes' stage C with the TP53 mutation did not show significant sensitivity to chemotherapy (c) (n = 11, P = 0.727), but patients with the TP53 mutation show a significant effect of chemotherapy (d)(n = 51, P = 0.026).

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BMC Cancer

ISSN: 1471-2407

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