Figure 5From: Selenium enrichment of broccoli sprout extract increases chemosensitivity and apoptosis of LNCaP prostate cancer cells Proposed schematic charts showing various mechanisms by which CSp and SeSp extracts inhibit LNCaP cell proliferation. Both extracts induced apoptosis through the extrinsic caspase-8 and intrinsic caspase-9 pathway. However, only the SeSp extract inhibited Akt phosphorylation and downstream mTOR phosphorylation, resulting in the inhibition of cell proliferation and survival.Back to article page