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Table 2 Multivariate Cox regression analysis of factors possibly influencing tumor-related survival and recurrence-free survival

From: Nuclear detection of Y-boxprotein-1 (YB-1) closely associates with progesterone receptor negativity and is a strong adverse survival factor in human breast cancer

     Tumor-related survival Recurrence-free survival
Name Variables   Categorisation Global Stepwise reverse selection Global Stepwise reverse selection
     p* Hazard ratio 95% Confidence interval p p* Hazard ratio 95% Confidence interval p
Model with dichotomous covariables
T Tumor stage 0 pT1-2 0.402   -   0.153   -  
   1 pT3-4         
N Lymp node status 0 pN0 0.002 5.050 2.264-11.267 <0.001 0.038 2.934 1.303-6.607 0.009
   1 pN1-3         
G Histologic grade 0 G1-2 0.136 1.875 0.946-3.715 0.072 0.007 3.188 1.442-7.052 0.004
   1 G3         
ER Estrogen receptor status 0 negative 0.168 0.420 0.213-0.829 0.012 0.047 0.357 0.173-0.733 0.005
   1 positive         
HER2 HER2 IHC 0 negative (0-1+) 0.386   -   0.045 2.164 1.019-4.594 0.045
   1 positive (2+-3+)         
CK5/6 Cytokeratin 5/6 IHC 0 negative (0) 0.085   -   0.305   -  
   1 positive (1+-3+)         
TP53 TP53 IHC 0 <10% 0.607   -   0.043 0.529 0.256-1.092 0.085
   1 ≥ 10%         
YB1 YB1 IHC 0 negative (0) 0.530   -   0.738   -  
  1 positive (1+-3+)