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Table 1 Baseline characteristics of study participants selected from the Danish Diet, Cancer and Health prospective cohort study.

From: Polymorphisms in the xenobiotic transporter Multidrug Resistance 1 (MDR1) and interaction with meat intake in relation to risk of colorectal cancer in a Danish prospective case-cohort study

 

Cases

Sub-cohort

IRRa (95% CI)

 

No. (%)

Median (5-95%)

No. (%)

Median (5-95%)

  

Total

359 (100)

 

765 (100)

   

Gender

      

   Men

200 (56)

 

419 (55)

   

   Women

159 (44)

 

346 (45)

   

Age at inclusion

 

59 (51-64)

 

56 (50-64)

  

Topology

      

   Proximal segment of colon

42 (12)

 

-

   

   Distal segment of colon

142 (40)

 

-

   

   Rectal

129 (36)

 

-

   

   Not specified

46 (13)

 

-

   

BMI, kg/m2

 

26 (21-34)

 

26 (20-33)

1.02b

(0.96-1.09)

Food intake

      

   Alcohol, g/day

 

14 (1-69)

 

13 (1-64)

1.06b

(1.00-1.13)

   Red meat, g/day

 

82 (36-170)

 

82 (32-175)

1.02b

(0.94-1.12)

   Processed meat, g/day

 

26 (6-80)

 

26 (4-78)

1.00b

(0.85-1.19)

   Dietary fibers g/day

 

20 (10-32)

 

21 (11-34)

0.62b

(0.37-1.02)

Smoking status at inclusion

      

   Never

111 (31)

 

262 (34)

 

1.00

-

   Former

112 (31)

 

239 (31)

 

1.02

(0.73-1.42)

   Present

136 (38)

 

264 (35)

 

1.15

(0.83-1.61)

NSAID use

      

   No

244 (68)

 

528 (69)

 

1.00

-

   Yes

115 (32)

 

237 (31)

 

1.07

(0.80-1.42)

HRT use among women

      

   Never

93 (58)

 

181 (52)

 

1.00

-

   Former

25 (16)

 

60 (17)

 

0.68

(0.39-1.18)

   Present

41 (26)

 

105 (30)

 

0.70

(0.44-1.10)

  1. a Mutually adjusted.
  2. b BMI pr. 2 kg/m2. Alcohol pr. 10 g/day. Red meat, processed meat and dietary fibers pr 25 g/day.
  3. Observed median values (5-95 percentiles) or percents of the distribution of alcohol, NSAID, smoking and potential colorectal cancer confounders among cases and members of the comparison group.