Int7G24A genotype | Cases (n = 504) | Controls (n = 504) | OR [95% CI] | p |
---|---|---|---|---|
Dominant model | number (%) | number (%) | ||
G/G | 296 (58.73) | 333 (66.07) | 1 (ref) | |
G/A and A/A | 208 (41.27) | 171 (33.93) | 1.37 [1.06-1.77] | 0.019* |
Additive model | ||||
G/G | 296 (58.73) | 333 (66.07) | 1 (ref) | |
G/A | 178(35.32) | 156 (30.95) | 1.28 [0.98-1.67] | |
A/A | 30 (5.95) | 15 (2.98) | 2.25 [1.20-4.23] | 0.005** |
Recessive model | ||||
G/G and G/A | 474 (94.05) | 489 (97.02) | 1 (ref) | |
A/A | 30 (5.95) | 15 (2.98) | 2.04 [1.11-3.85] | 0.032* |
≤ 70 yrs (n = 213) | ≤ 70 yrs (n = 219) | |||
G/G, number (%) | 118 (55.40) | 150 (68.49) | 1 (ref) | |
G/A, number (%) | 80 (37.56) | 61 (27.85) | 1.67 [1.11-2.51] | |
A/A, number (%) | 15 (7.04) | 8 (3.65) | 2.38 [1.00-5.68] | 0.004** |
>70 yrs (n = 227) | >70 yrs (n = 284) | |||
G/G, number (%) | 145 (63.88) | 182 (64.08) | 1 (ref) | |
G/A, number (%) | 72 (31.72) | 95 (33.45) | 0.95 [0.65-1.39] | |
A/A, number (%) | 10 (4.41) | 7 (2.46) | 1.79 [0.69-4.67] | 0.662** |
males (n = 295) | males (n = 226) | |||
G/G, number (%) | 166 (56.27) | 160 (70.80) | 1 (ref) | |
G/A, number (%) | 112 (37.97) | 62 (27.43) | 1.74 [1.19-2.54] | |
A/A, number (%) | 17 (5.76) | 4 (1.77) | 4.10 [1.41-11.85] | 0.00023** |
females (n = 202) | females (n = 277) | |||
G/G, number (%) | 126 (62.38) | 172 (62.09) | 1 (ref) | |
G/A, number (%) | 63 (31.19) | 94 (33.94) | 0.92 [0.62-1.36] | |
A/A, number (%) | 13 (6.44) | 11 (3.97) | 1.61 [0.71-3.65] | 0.688** |