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Table 1 Viability of non-stimulated and PHA-stimulated blood cells treated with etoposide as determined by dual-cell stain method.

From: DNA-AP sites generation by Etoposide in whole blood cells

Etoposide

2 h treatment non-stimulated blood cells

2 h treatment PHA-stimulated blood cells

0 μM

100 ± 5.5

100 ± 5.6

2.07 μM

95.5 ± 8.5

88.6 ± 3.9

20.7 μM

99.2 ± 2.2

83.2 ± 8.2

207 μM

91.1 ± 8.2

75.6 ± 7.6

Etoposide

24 h treatment non-stimulated blood cells

24 h treatment PHA-stimulated blood cells

0 μM

100 ± 2.3

100 ± 3.9

2.07 μM

100 ± 3.7

96.7 ± 3.4

20.7 μM

100 ± 8.0

96.7 ± 3.4

207 μM

93.8 ± 8.2

81.4 ± 9.9

  1. Viability % ± SD. Each cell represents the average of three independent experiments.