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Figure 3 | BMC Cancer

Figure 3

From: High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo

Figure 3

Effects of SAHA and VPA on IκBα protein level and histone acetylation in PANC-1. Western Blot showing acetylated histone H3 as well as protein levels of IκBα, p-IκBα and β-Actin in response to SAHA (8 μM) and VPA (8 mM) treatment. HDI treatment led to an increase of histone H3 acetylation and markedly diminished phosphorylation of IκBα.

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