Skip to main content
Figure 1 | BMC Cancer

Figure 1

From: High class I HDAC activity and expression are associated with RelA/p65 activation in pancreatic cancer in vitro and in vivo

Figure 1

HDAC1, HDAC2 and HDAC3 as well as RelA/p65 expression in pancreatic carcinomas. (A/C/E/G) Serial sections of a pancreatic ductal adenocarcinoma infiltrating a lymph node. Note strong expression of HDAC1 (A), HDAC2 (C), HDAC3 (E) and nuclear positivity for RelA/p65 (G). Magnification ×100. (B/D/F/H) Serial sections of a ductal pancreatic adenocarcinoma showing nuclear positivity for HDAC1 (B), HDAC2 (D) and HDAC3 (F). Strong expression of the three isoforms is accompanied by strong nuclear translocation of RelA/p65 (H). Weak cytoplasmic RelA/p65 positivity can be seen in this case, as well. Magnification ×400.

Back to article page