Table 3 Effect of demographic and clinical parameters on disease free survival in the initial training set
Variable Name | Coefficient | p-value | Variable Name | Coefficient | p-value |
|---|---|---|---|---|---|
Poly (age,2) | - | 0.32 | Gender, male | 0.114 | 0.605 |
age | -0.06 | 0.20 | Family history | 0.304 | 0.13 |
age2 | 0.0005 | 0.16 | Smoking | ||
Liver function parameters | No | -0.476 | 0.06 | ||
AFP [log10] (ng/mL) | 0.107 | 7.5e-5 | Moderate | -0.414 | 0.12 |
SGPT (U/L | -0.0001 | 0.91 | Heavy | ref | Ref |
SGOT (U/L) | 0.003 | 0.02 | Alcohol Drinking | ||
BILIRUBIN (μM) | 0.002 | 0.72 | No | 0.009 | 0.97 |
ALBUMIN (mg/mL) | -0.030 | 0.04 | Moderate | 0.117 | 0.67 |
Venous Infiltration | 1.06 | 3.0e-09 | Heavy | ref | ref |
Non-tumorous liver histology | 0.97 | No. of tumor nodule(s) | |||
Tumor size | -0.012 | 0.04 | 1 | ref | ref |
pTNM Stage | 2 | 0.611 | 0.05 | ||
I | 0.302 | 0.56 | 3~6 | 0.500 | 0.39 |
II | Ref | Ref | Multiple >6 | 0.963 | 1.1e-5 |
III | 0.924 | 8.7e-06 | |||
IV | 1.20 | 2.8e-07 | Child's grade, B | 0.359 | 0.48 |
AJCC Stage | |||||
I | ref | ref | Edmondson Grade | - | 0.29 |
II | 0.67 | 2.6e-03 | HBsAg + | -0.007 | 0.98 |
III & IV | 1.16 | 2.1e-08 |