From: Association between an 8q24 locus and the risk of colorectal cancer in Japanese
 |  |  |  |  | Allelic model | Genotype model | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 |  |  |  |  | Model 1 *1 |  |  | Model 2 *2 |  |  | Heterozygote |  |  | Minor homozygote |  |  |
8q24 locus | Â | Genotype | Â | Â | OR | 95% CI | p-value | ORa | 95% CI | p-value | ORa | 95% CI | p-value | ORa | 95% CI | p-value |
rs6983267 (Minor allele: G, MAF*1 in controls = 0.338) | ||||||||||||||||
 | TT | TG | GG | UK*4 |  |  |  |  |  |  |  |  |  |  |  |  |
case/control | 181/418 | 222/436 | 73/107 | 3/1 | 1.22 | 1.04-1.44 | 0.0144 | 1.25 | 1.06-1.48 | 0.0071 | 1.19 | 0.93-1.52 | 0.1665 | 1.64 | 1.15-2.35 | 0.0063 |
rs10090154 (Minor allele: T, MAF in controls = 0.153) | ||||||||||||||||
 | CC | CT | TT | UK |  |  |  |  |  |  |  |  |  |  |  |  |
case/control | 355/689 | 112/247 | 11/23 | 3/3 | 0.90 | 0.72-1.12 | 0.3443 | 0.87 | 0.69-1.09 | 0.2140 | 0.83 | 0.63-1.08 | 0.1690 | 0.90 | 0.43-1.89 | 0.7854 |