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Table 4 Validation of selected genes in an independent set of 47 tissues by real time PCR

From: Expression profiling identifies genes involved in neoplastic transformation of serous ovarian cancer

  

Fold change (± SD)1

Kruskal Wallis p-Values

Genbank Acc. No.

Gene name

LMP2 vsnormal/benign

Invasive vsnormal/benign

LMP2 vsnormal/benign

Invasive vsnormal/benign

Invasive vsLMP†

NM_030651

C6orf31 3

0.37 ± 0.52

0.19 ± 0.49

NS, p = 0.13

p < 0.01

p < 0.05

NM_015710

GLTSCR2 4

0.51 ± 0.61

0.17 ± 0.22

NS, p = 0.17

p < 0.01

p < 0.01

NM_006206

PDGFRA 4

0.31 ± 0.51

0.15 ± 0.22

P < 0.05

p < 0.01

NS, p = 0.13

NM_003064

SLPI

3.86 ± 1.80

5.70 ± 4.20

P < 0.05

p < 0.05

NS, p = 0.95

NM_004625

WNT7A

180.0 ± 250.0

150.0 ± 205.0

P < 0.01

p < 0.001

NS, p = 0.67

  1. 1Real time PCR results were calculated using the Pfaffl (2001) method with B2M as the reference gene. 2Low malignant potential. 3Outlier (00231) removed from analysis. 4Outliers (44286, 44428) removed from analysis.