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Table 1 Patient Characteristics before and after Surgery (n = 119)

From: Retrospective analysis of 119 Chinese noninflammatory locally advanced breast cancer cases treated with intravenous combination of vinorelbine and epirubicin as a neoadjuvant chemotherapy: a median follow-up of 63.4 months

Characteristics

No.(%)

Characteristics

No.(%)

Clinical stage

 

Grade

 

   II B

32 (26.9%)

   I

1 (0.8%)

   III A

56 (47.1%)

   II

67 (56.3%)

   III B

22 (18.5%)

   III

15 (12.6%)

   III C

9 (7.5%)

   Not graded

36 (30.3%)

Pre-cALN

 

Post-cALN

 

   negative

36 (30.3%)

   negative

81 (68.1%)

   positive

83 (69.7%)

   positive

38 (31.9%)

Pre-ER

 

Post-ER※

 

   negative

58 (48.7%)

   negative

82 (75.2%)

   positive

61 (51.3%)

   positive

27 (24.8%)

Pre-PR

 

Post-PR※

 

   negative

60 (50.4%)

   negative

84 (77.1%)

   positive

59 (49.6%)

   positive

25 (22.9%)

Pre-HER-2

 

Post-HER-2※

 

   0-2+

86 (72.3%)

   0-2+

79 (72.5%)

   3+

33 (27.7%)

   3+

30 (27.5%)

Pre-Ki67

 

Post-Ki67※

 

   ≤ 20%

74 (62.2%)

   ≤ 20%

93 (85.3%)

   >20%

45 (37.8%)

   >20%

16 (14.7%)

Pathology

 

Pathological tumor size

 

   IDC

92 (77.3%)

   ≤ 2 cm

28 (23.5%)

   ILC

4 (3.4%)

   > 2 cm

59 (49.6%)

   other

23 (19.3%)

   unmeasured

32 (26.9%)

Clinical response

 

pALN

 

   CR

27 (22.7%)

   N 0

39 (32.8%)

   PR

78 (65.6%)

   N 1-3

24 (20.2%)

   SD

13 (10.9%)

   N 4-9

35 (29.4%)

   PD

1 (0.8%)

   N >9

21 (17.6%)

Pathological response in tumor site

   

   T-A

22 (18.5%)

  

   T-B

75 (63.0%)

  

   T-C

22 (18.5%)

  
  1. Abbreviations: pre-, before chemotherapy; post-, after chemotherapy; cALN, clinical axillary lymph node; pALN: pathological axillary lymph node; IDC: Invasive ductal cancer; ILC: Invasive lobular cancer; CR, Complete response; PR, Partial response; SD, Stable disease; PD, Progressive disease; T-A: no tumor cell or presence of in situ carcinoma, no invasive tumor; T-B: presence of invasive carcinoma without special involvement (such as skin, vessel, more than one quadrant); T-C: presence of invasive carcinoma with special involvement.
  2. ※109 patients were evaluated after neoadjuvant chemotherapy, because of 10 patients with no residual tumor in postoperative tissue.