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Table 2 Risk for esophagus (ICD-9: 150), stomach (ICD-9: 151), colon (ICD-9:153) and rectum (ICD-9: 154) as the second primary cancer site among 33,787 oral/pharyngeal cancer (ICD-9: 140-149, except 142 and 147) patients.

From: The incidence and risk of developing a second primary esophageal cancer in patients with oral and pharyngeal carcinoma: a population-based study in Taiwan over a 25 year period

First primary cancer site (ICD-9)

  

Esophagus

Stomach

Colon

Rectum

 

Sex

OPY

O

E

SIR

(95% CI)

O

E

SIR

(95% CI)

O

E

SIR

(95% CI)

O

E

SIR

(95% CI)

Oral cavity

(140-1, 143-5)

All

90644

99

17.73

5.57

(4.53-6.78)

28

48.02

0.58

(0.39-0.84)

39

41.63

0.93

(0.66-1.28)

35

36.15

0.97

(0.67-1.34)

 

M

77527

99

17.25

5.74

(4.66-6.99)

28

42.82

0.65

(0.43-0.95)

31

34.68

0.89

(0.61-1.27)

29

30.90

0.94

(0.63-1.35)

 

F

13117

0

0.48

0

(NA)

0

5.20

0

(NA)

8

6.95

1.15

(0.50-2.27)

6

5.25

1.14

(0.42-2.49)

Oropharynx

(146,149)

All

11303

30

2.11

14.29

(9.64-20.39)

2

6.51

0.31

(0.03-1.11)

0

5.63

0

(NA)

3

4.77

0.63

(0.13-1.83)

 

M

8474

29

2.01

14.43

(9.66-20.72)

0

5.48

0

(NA)

0

4.25

0

(NA)

3

3.73

0.80

(0.16-2.35)

 

F

2829

1

0.09

11.11

(0.15-61.82)

2

1.03

1.94

(0.22-7.01)

0

1.38

0

(NA)

0

1.04

0

(NA)

Hypopharynx

(148)

All

11212

71

3.12

22.76

(17.77-28.70)

6

9.40

0.64

(0.23-1.39)

7

7.18

0.97

(0.39-2.01)

8

6.18

1.29

(0.56-2.55)

 

M

10721

69

3.09

22.33

(17.37-28.26)

6

9.17

0.65

(0.24-1.42)

6

6.87

0.87

(0.32-1.90)

8

5.95

1.34

(0.58-2.65)

 

F

491

2

0.02

100

(11.23-361.05)

0

0.23

0

(NA)

1

0.30

3.33

(0.04-18.55)

0

0.23

0

(NA)

  1. Bold indicates statistical significance.
  2. OPY = observed person years; SIR = standardized incidence ratio; O = observed numbers of second primary cancers; E = expected numbers of second primary cancers; CI = confidence interval; NA = not assessable.