Clinical relevance of nine transcriptional molecular markers for the diagnosis of head and neck squamous cell carcinoma in tissue and saliva rinse

Table 4 Diagnostic values of the 9 gene of interest

Gene	AUC	Cut-off value	False negative	False positive	True negative	True positive	Sensitivity (%)	Specificity (%)
FN1	0,693	0.20	19	11	35	27	58.7	76.1
IL1NR	0,974	0.51	3	2	44	43	93.5	95.7
KTR13	0,921	4.80	1	11	33	42	75.0	95.5
KTR4	0,947	0.23	5	4	42	41	89.1	91.3
MAL	0,986	0.72	2	4	42	44	95.7	91.3
MMP1	0,989	24.00	3	1	45	43	93.5	97.8
PLAU	0,897	2.30	9	5	41	37	80.5	89.1
SPARC	0,864	0.67	13	3	43	33	71.7	93.5
TGM3	0,939	0.31	7	4	42	39	84.8	91.3

Calculation of AUC values for the relative expression levels of the nine genes of interest by ROC analyses and the corresponding diagnostic values with optimum cut-off value.

ISSN: 1471-2407