Figure 2

Frequency plots. A) Frequency plot of chromosome arm 3q. The significant region in 3q26.2 is highlighted in grey. B) Example of one case exhibiting a SRO gain peak in the significant region 3q26.2 only. BAC clone segments are matched to their size. All genes in the region are displayed and those in the significant region are highlighted in yellow. C) Frequency plot of chromosome X. The significant regions are highlighted in grey, and the gene SH3KBP1 that was explored with QPCR is shown. D) Frequency plot of chromosome 9. The significant regions are highlighted in grey, and the gene SH3GL2 that was explored with QPCR is shown. In all frequency plots: resistant cases (black line) versus sensitive cases (red line).