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Table 6 Relation between breast cancer receptorial status and BRCA1 mutant genotype excluding HER2 3+ cases.

From: Selecting for BRCA1 testing using a combination of homogeneous selection criteria and immunohistochemical characteristics of breast cancers

Receptorial status BRCA1 carriers non-BRCA1 cases Total
° ER- and/or PR- 10 12 22
ER+/PR+ - 60 60
Total 10 72 82
  1. Sensitivity 100%; Specificity 83.3%; Predictive Positive Value 45.4%; Predictive Negative Value 100%; ° IHC Allred total scores of 3 or more were reported as positive.