Figure 1
From: ST3Gal.I sialyltransferase relevance in bladder cancer tissues and cell lines
Bladder cancer tissue has increased expression of ST3Gal.I. The relative mRNA levels of ST3Gal.I (A), ST3Gal.II (B) and ST3Gal.IV (C) genes were analyzed by Real Time RT-PCR as described in the Methods section, in bladder tumor tissue (T) and corresponding normal urothelium (U) from patients with nonmuscle-invasive (I), with invasive (II) and with non malignant bladder tumors (III). Values infer the number of mRNA molecules of a certain gene per 1000 molecules of the average of the endogenous controls (β-actin and GAPDH). ST3Gal.I expression is significantly increased in tissue of nonmuscle-invasive bladder cancer (I), compared with the corresponding urothelium (p < 0.001).