Figure 1From: The influence of P-glycoprotein expression and its inhibitors on the distribution of doxorubicin in breast tumors Distribution of doxorubicin in solid tumors. Murine tumors EMT6 (A) and its PgP overexpressing subline AR1 (B) and MCF-7 human breast cancer xenograft (C) and its PgP overexpressing subline BC19 (D) were resected from Balb/C and nude mice, respectively. Doxorubicin is shown in blue and blood vessels are shown in red. Note more uniform distribution of doxorubicin in the PgP overexpressing tumors. (Scale bars = 100 μm)Back to article page