Table 5 Somatic mutations in BRAF, NRAS, and p16CDKN2Agenes among in vivo melanoma tissues
Case | Sex | Age at diagnosis | Primary tumour | Lymph node metastasis | ||||
|---|---|---|---|---|---|---|---|---|
| Â | Â | Â | BRAF | NRAS | p16 CDKN2A | BRAF | NRAS | p16 CDKN2A |
MN01 | M | 43 | Â | Â | Â | L597R | Â | Â |
MN02 | F | 63 | Â | Q61R | Â | Â | Q61R | Â |
MN03 | M | 51 | V600E | Â | Â | V600E | Â | Â |
MN04 | M | 40 | V600E | Â | Â | V600E | Â | Â |
MN06 | M | 49 | V600E | Â | Â | V600E | Â | Â |
MN07 | M | 39 | V600E | Â | Â | V600E | Â | Â |
MN08 | F | 65 | Â | Q61R | Â | Â | Q61R | Â |
MN09 | M | 34 | Â | Q61R | Â | Â | Q61R | Â |
MN10 | M | 67 | V600E | Â | Arg24Pro | V600E | Â | Arg24Pro |
MN11 | M | 84 | V600K | Â | Â | V600K | Â | Â |
MN12 | M | 74 | Â | Â | Â | Â | Â | Â |
MN14 | M | 41 | Â | Â | n.t. | Â | Â | Â |
MN15 | M | 63 | Â | Â | Â | Â | Â | Arg80ter |
MN18 | M | 75 | Â | Â | Â | Â | Â | Â |
MN19 | M | 30 | V600E | Â | Â | V600E | Â | Â |
MN20 | F | 45 | V600E | Â | Â | V600E | Â | Â |
MN21 | M | 35 | Â | Â | Ala36Thr | Â | Â | Ala36Th |
MN22 | M | 71 | Â | Q61R | Â | Â | Q61R | Â |
MN25 | F | 35 | V600E | Â | Â | V600E | Â | Â |
MN26 | M | 50 | Â | Q61R | Â | Â | Q61R | Â |
MN27 | F | 48 | Â | Â | Â | Â | Â | Â |
MN28 | F | 58 | Â | Q61K | Â | Â | Q61K | Â |
MN29 | M | 51 | V600E | Â | Â | V600E | Â | Â |
MN31 | M | 40 | Â | Q61R | Â | Â | Q61R | Â |
MN34 | F | 65 | Â | Q61R | Ala109Val | Â | Q61R | Ala109Val |
MN35 | M | 61 | Â | Â | Â | Â | Â | Â |
MN36 | M | 64 | Â | Â | Trp110ter | Â | Â | Trp110ter |
MN41 | F | 69 | Â | Â | Â | Â | Â | Â |
MN45 | F | 56 | n.t. | n.t. | n.t. | Â | Â | Arg80ter |
MN05 | M | 51 | V600E | Â | Â | V600E | Â | IVS1+1G>A |
MN55 | F | 34 | Â | Â | Â | Â | Â | Â |
MN56 | F | 36 | V600E | Â | Â | V600E | Â | Â |
MN59 | F | 53 | Â | Q61K | Â | Â | Q61K | Â |
MN68 | M | 45 | Â | Q61R | Â | Â | Q61R | Â |
MN75 | F | 56 | Â | Q61R | Arg24Pro | Â | Q61R | Arg24Pro |