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Figure 4 | BMC Cancer

Figure 4

From: Tumor suppressor protein SMAR1 modulates the roughness of cell surface: combined AFM and SEM study

Figure 4

AFM images showing smooth topography in normal tissues compared to the cancerous tissue sections. (A) AFM images of tumor sections from nude mice. Height, processed, 3D and profile (of line shown in height image) of tumor sections from control (x-y range 20 × 20 μm, z range 1.7 μm) and SMAR1-P44 (x-y range 30 × 30 μm, z range 4.7 μm) treated mice are shown. (B) AFM images of human breast cancer sections. Height image and profile (line shown in height image) of tumor sections from normal breast tissue (x-y range 10 × 10 μm, z range 0.84 μm); Grade I (x-y range 10 × 10 μm, z range 1.17 μm), Grade II (x-y range 10 × 10 μm, z range 1.4 μm) and Grade III (x-y range 10 × 10 μm, z range 2.65 μm) tumors and Giant multinucleated cells (x-y range 30 × 30 μm, z range 10.8 μm) are shown.

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