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Figure 1 | BMC Cancer

Figure 1

From: Tumor suppressor protein SMAR1 modulates the roughness of cell surface: combined AFM and SEM study

Figure 1

Cells overexpressing SMAR1 exhibit smooth surface morphology as shown by SEM images. (A) Images of control, SMAR1 and SMAR1-siRNA transfected (transient) human embryonic kidney cell line (HEK 293) (photographs taken at lower magnification of 3000 × and higher magnifications of 8,500 × for control and SMAR1-siRNA treated cells and 12000 × for SMAR1 treated cells); (B) RT-PCR and (C) Western blotting results showing the expression of SMAR1 in control, SMAR1 and SMAR1-siRNA transfected HEK 293 cell line wherein actin has been used as the loading control. (D) SEM images of control and SMAR1 stably transfected mouse melanoma cell line (B16F1) (photographs taken at lower magnifications of 1000 × and 3000 ×; and higher magnifications of 8000 × for control and 8,500 × for SMAR1 treated cells).

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