| | |
RCAS1 immunoreactivity
|
|
Variables
|
Number
|
-
|
+1
|
+2
|
+3
|
|
Pharyngeal and laryngeal squamous cell carcinoma
|
51
|
0
|
0
|
22 (44%)
|
29 (56%)
|
|
Clear surgical margin
|
51
|
1
(3.5%)
|
24 (44.5%)*
|
25 (48.5%)*
|
1
(3.5%)
|
- *The change in the intensity of immunoreactivity was observed in six specimens (12%), in one case in the group of the +1 RCAS1 immunoreactivity and in 5 cases in the group of +2 RCAS1 immunoreactivity; the expression decreased with the distance from cancer cells. In four examined samples, the RCAS1 immunoreactivity level in closely tumor-adjacent tissue was established as moderate and decreasing to weak in the line of resection. In two cases, weak RCAS1 immunoreactivity in the directly tumor-adjacent tissue diminished to the point of absence in the resection line.
