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Table 5 Relative risk (RR) and 95% confidence intervals (CI) for the association of moderate-to-vigorous physical activity during four periods of life with breast cancer incidence: 118,899 postmenopausal women in the NIH-AARP Diet and Health Study

From: Intensity and timing of physical activity in relation to postmenopausal breast cancer risk: the prospective NIH-AARP Diet and Health Study

Moderate-to-vigorous activity No.
cancers*
n = 4287
RR 95%
CI
RR†† 95%
CI
RR§ 95%
CI
RR£ 95%
CI
Ages 15-18 years             
   Never/Rarely 541 1.00 (ref.)   1.00 (ref.)    1.00 (ref.)    1.00 (ref.)   
   <1 hour/week 394 1.11 0.98, 1.27 1.12 0.98 1.27 1.10 0.97 1.26 1.12 0.98 1.27
   1-3 hours/week 936 1.05 0.95, 1.17 1.05 0.94 1.17 1.04 0.93 1.16 1.05 0.94 1.16
   4-7 hours/week 950 1.02 0.92, 1.14 1.01 0.91 1.13 1.00 0.89 1.12 1.01 0.91 1.13
   >7 hours/week 1415 1.02 0.92, 1.12 1.03 0.93 1.14 1.02 0.91 1.14 1.02 0.93 1.13
Ages 19-29 years             
   Never/Rarely 415 1.00 (ref.)   1.00 (ref.)    1.00 (ref.)    1.00 (ref.)   
   <1 hour/week 384 1.09 0.95, 1.25 1.08 0.94 1.24 1.07 0.93 1.23 1.08 0.94 1.24
   1-3 hours/week 976 1.07 0.95, 1.20 1.06 0.94 1.19 1.05 0.93 1.18 1.06 0.94 1.19
   4-7 hours/week 1080 1.00 0.89, 1.12 1.01 0.90 1.13 1.01 0.89 1.13 1.01 0.90 1.13
   >7 hours/week 1375 0.97 0.87, 1.08 1.01 0.90 1.13 1.02 0.90 1.15 1.01 0.90 1.13
Ages 35-39 years             
   Never/Rarely 392 1.00 (ref.)   1.00 (ref.)    1.00 (ref.)    1.00 (ref.)   
   <1 hour/week 421 1.12 0.98, 1.28 1.11 0.97 1.27 1.09 0.95 1.25 1.11 0.97 1.27
   1-3 hours/week 963 1.00 0.89, 1.13 0.99 0.88 1.11 0.98 0.87 1.11 0.99 0.88 1.12
   4-7 hours/week 1174 1.03 0.92, 1.16 1.03 0.92 1.15 1.04 0.92 1.18 1.04 0.93 1.16
   >7 hours/week 1288 0.94 0.84, 1.06 0.97 0.87 1.09 0.99 0.87 1.12 0.98 0.88 1.10
Past 10 years             
   Never/Rarely 646 1.00 (ref.)   1.00 (ref.)    1.00 (ref.)    1.00 (ref.)   
   <1 hour/week 507 1.06 0.94, 1.19 1.05 0.94 1.18 1.03 0.92 1.16 1.06 0.94 1.19
   1-3 hours/week 1071 0.93 0.84, 1.02 0.91 0.83 1.00 0.90 0.81 1.00 0.93 0.84 1.02
   4-7 hours/week 1106 0.94 0.86, 1.04 0.92 0.83 1.01 0.91 0.82 1.01 0.94 0.85 1.04
   >7 hours/week 928 0.84 0.76, 0.93 0.84 0.76 0.93 0.85 0.76 0.95 0.87 0.78 0.96
  1. Number of cancer cases may not add up to total (n = 4287) due to missing physical activity values
  2. † Relative risks adjusted for age (continuous)
  3. †† Relative risks adjusted for: age (continuous); race/ethnicity (white, black, Hispanic, Asian/Pacific Islander/American Indian); education level (<12 years or high school equivalent, 12 years or high school equivalent, post-high school vocational or technical training, some college, college graduate, post-graduate); smoking status (non-smoker, former, current); alcohol intake (grams/day, quintiles adjusted for total energy intake); family history of breast cancer (no, yes); age at menarche (<13, 13-14, ≥ 15 years); age at first birth (nulliparous, <20, 20-24, 25-29, 30+ years); parity (number of children: 0, 1-2, 3 or more); age at menopause (<40, 40-44, 45-49, 50-54, ≥ 55 years); menopausal hormone use (never, ever)
  4. §Relative risks additionally adjusted for frequency of other type of physical activity (either light or moderate-to-vigorous) during that same time period
  5. £ Relative risks additionally adjusted for body mass index (BMI: <25.0, 25.0-29.9, 30.0-34.9, ≥ 35.0 kg/m2)