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Table 1 Clinicopathologic characteristics of study population

From: Adjuvant concurrent chemoradiation therapy (CCRT) alone versus CCRT followed by adjuvant chemotherapy: Which is better in patients with radically resected extrahepatic biliary tract cancer?: a non-randomized, single center study

   Total patients CCRT CCRT followed by adjuvant chemotherapy P + value
Case   120 30 90  
Median age, years (range) 62.4 (24.2~87.0) 63.4 (24.2~74.4) 62.1 (38.8~87.0) 0.87
Men (%)   89 (74.2) 20 (66.7) 69 (76.7) 0.25
Performance ECOG 0-1 111 (92.5) 28 (93.3) 83 (92.2) 0.73
  ECOG 2 9 (7.5) 2 (6.7) 7 (7.8)  
T stage (%) T1 20 (16.7) 4 (13.3) 16 (17.8) 0.53
  T2 33 (27.5) 6 (20.0) 27 (30.0)  
  T3 51 (42.5) 16 (53.3) 35 (38.9)  
  T4 16 (13.3) 4 (13.3) 12 (13.3)  
N stage (%) N0 77 (64.2) 18 (60.0) 59 (65.6) 0.58
  N1 43 (35.8) 12 (40.0) 31 (34.4)  
Stage (%) IA 13 (10.8) 2 (6.7) 11 (12.2) 0.73
  IB 27 (22.5) 5 (16.7) 22 (24.4)  
  IIA 29 (24.2) 9 (30.0) 20 (22.2)  
  IIB 35 (29.2) 10 (33.3) 25 (27.8)  
  III 16 (13.3) 4 (13.3) 12 (13.3)  
RM status (%) Negative 79 (65.8) 19 (63.3) 60 (66.7) 0.74
  Positive 41 (34.2) 11 (36.7) 30 (33.3)  
CA 19-9 (%) ≤ 60 U/ml 57 (47.5) 17 (56.7) 40 (44.4) 0.27
  > 60 62 (51.7) 13 (43.3) 49 (54.4)  
Tumor location (%) Proximal 59 (49.2) 13 (43.3) 46 (51.1) 0.52
  Distal 55 (45.8) 15 (50.0) 40 (44.4)  
Histologic grade (%) WD/MD 107 (89.2) 29 (96.7) 78 (86.7) 0.29
  PD 11 (9.2) 1 (3.3) 10 (11.1)  
Recurrence (%) Local 22 (32.4) 5 (26.3) 17 (34.7) 0.51
  Systemic 46 (67.6) 14 (73.7) 32 (65.3)  
  1. +Statistical value between CCRT and CCRT followed by adjuvant chemotherapy
  2. ECOG, Eastern Cooperative Oncology Group; RM, resection margin; WD, well differentiated; MD, moderate differentiated; PD, poor differentiated; CCRT, concurrent chemoradiation therapy.