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Table 2 Immunohistochemical expression of thymidylate synthase (TS) and topoisomerase I (Topo I) in tumor tissue samples (N = 498).

From: Topoisomerase I but not thymidylate synthase is associated with improved outcome in patients with resected colorectal cancer treated with irinotecan containing adjuvant chemotherapy

TS score

N

%

 

0

157

32

 

1

1

0.2

Negative/Low

2

47

9

expression

3

73

15

 

4

105

21

 

5

60

12

Positive/High

6

47

9

expression

Non Evaluable

8

2

 

Topo I score

   

0

170

34

 

2

19

4

Negative/Low

3

54

11

expression

4

126

25

 

5

80

16

Positive/High

6

32

6

expression

Non Evaluable

17

3

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