Effects of a PI3K inhibitor on invasion and MMP secretion of FHCC98 and 7721 cells. (A-C) Matrigel invasion assay of FHCC98 (A, B) and 7721 (A, C) cells. (D-F) MMP levels of FHCC98 (D, E) and 7721 (D, F) cells. Bars represent the mean of triplicate samples; error bars represent standard deviation. Data are representative of three independent experiments. * P < 0.05 versus corresponding untreated cells.