Expression of mRNAs for ERα, ERβ1 (wild type) and two truncated ERβ variants (ERβ2 and ERβ5) in grade 1 endometrial cancers. Samples n = 10 per group, concentrations were normalised against those of an internal control sample. A, ERα, note that the amount of mRNA was significantly lower (p < 0.0001) in samples graded as poor compared with those that were well or moderately differentiated; B, ERβ1 (full length wild-type); C, ERβ2 (ERβcx); D, ERβ5. There was no statistically significant difference between the levels of expression of ERβ variants between the different groups. Significant differences between samples are indicated with letters a, b.