Skip to main content

Table 1 Distribution of "very early" and "early" HCC, according to the different variables.

From: Early and very early hepatocellular carcinoma: when and how much do staging and choice of treatment really matter? A multi-center study

   Very EarlyHCC (65) EarlyHCC (465)
Variables   N % N %
Gender Male (M) 43 66 316 68
  Female (F) 22 34 149 32
Age < 60 16 24 107 23
  60 – 70 31 48 214 46
  > 70 18 28 144 31
Disease Aetiology HBV 4 6 42 9
  HCV 44 68 274 59
  Alcohol abuse 7 11 51 11
  Alcohol and virus 4 6 56 12
  Mixed and others 6 9 42 9
HCC diagnosis Incidental 6 9 116 25
  Surveillance 58 89 326 70
  Symptomatic 1* 2 23* 5
Alfafetoprotein < 20 ng/ml 31 47 228 49
  20–200 ng/ml 27 42 205 44
  > 200 ng/ml 7 11 32 7
Bilirubin < 2 mg/dl 62 95 398 85
  ≥2 mg/dl 3 5 67 15
Lesion number 1 65 100 344 74
  2–3 0 0 121 26
Tumor size ≤2 cm 65 100 158 34
  2–3 cm 0 0 202 43
  > 3 cm 0 0 105 23
Child-Pugh class A 65 100 331 71
  B 0 0 134 29
CLIP score 0 61 93 243 52
  1 4 7 167 36
  2 0 0 47 10
  3 0 0 8 2
Type of treatment OLTx 3 5 11 2
  RESECTION 8 12 75 16
  RFTA 14 22 58 12
  PEI 20 30 106 23
  TACE 17 26 128 28
  PEI + TACE - - 25 6
  BSC 3 5 62 13
  1. OLTx: orthotopic liver transplantation; RFTA: radiofrequency-mediated thermal ablation;
  2. PEI: percutaneous ethanol injection; TACE: transcatheter arterial chemoembolization; BSC: best supportive care.