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Table 3 Expression profile of AP-1 proteins in immunoblotting and densitometric analysis of their level of expression in normal adjacent controls and tumor tissues of ESCC.

From: Transcription factor AP-1 in esophageal squamous cell carcinoma: Alterations in activity and expression during Human Papillomavirus infection

AP-1 Family Member Protein Normal
(n = 75)
Cancer
(n = 75)
p-value
  Nil Weak Medium Strong Nil Weak Medium Strong  
cJun 10 23 42 - - 5 24 46 0.001
JunB 49 16 8 2 2 9 30 34 0.001
JunD 53 20 2 - - 7 21 47 0.001
cFos 69 6 - - - - 13 62 0.001
FosB 4 8 36 27 2 14 29 30 0.52
Fra-1 35 12 19 9 11 17 10 37 0.003
Fra-2 5 5 28 37 11 16 18 30 0.002
  1. Arbitrary level of expression in Immunoblotting: strong =>50%; medium = 10-50%; Weak = 1-10%; and Nil/undetectable =< 1%. Statistical calculation was done by grouping nil & weak, medium & strong together. Yates corrected chi-square/Fishers exact test were performed.